Kathmandu. For millions of people around the world, hair loss is always frustrating. Drugs and surgeries on the market either work slowly or are expensive. But now scientists at the University of California, Los Angeles (UCLA) have found a revolutionary solution that could change the entire process of hair restoration.
A team of researchers at UCLA has identified a small molecule called AA405. This can activate the roots of the dormant hair and start natural hair growth immediately.
How does this new drug work?TAG_OPEN_strong_42
The most exciting aspect of the AA405 is its functioning. This is different from older treatments.
Medications such as minoxidil and finasteride either block hormones or increase blood flow and slow down the process of hair loss.TAG_CLOSE_span_39 TAG_OPEN_span_39
New scientific trick: AA405 directly targets stem cells at the root of the hair. Scientists have found that when hair does not grow, the metabolic activity of these cells slows down. AA405 turns this metabolic switch back on. This pushes the roots out of the ‘sleeping state’ and into the ‘growth stage’.
Hair transplant surgeon Dr. Experts such as Gary Linkov hailed the new cellular mechanism as the biggest leap forward in hair loss in decades.
Encouraging test results and business initiatives
William Lowery, Heather Kristof, and Michael Jung, researchers at UCLA who were involved in the development of AA405, said they were surprised by the results of the initial study.
Success in animals: In mice, it was found to regrow strong hair within a few days.
Human trials: Early-stage human trials conducted by Pelage Pharmaceuticals have also shown positive results. According to a report, 31% of men who used AA405 had more than 20% hair density within 8 weeks. However, there was no improvement in the placebo group. This gives a strong indication of new hair growth.
The company aims to start large-scale studies by 2026. This will pave the way for this treatment to be brought to market.
Let’s not rush into a final decision{
The potential impact of AA405 is extraordinary. It can provide an alternative to expensive surgeries for millions of people and help boost self-confidence. Science, however, requires a balanced approach.
Long-term safety: Experts have been emphasizing that data from a variety of backgrounds and long-term periods is needed before the drug is ready for use. Larger trials are needed to ensure its long-term safety and efficacy.
Current status: The TAG_CLOSE_span_32 AA405 is not currently available on the market and is in full testing.
However, the treatment for hair loss seemed to be “stuck in one place” for decades. Now the rise of molecules like AA405 proves that science is indeed redefining the future of hair restoration. We are all waiting for its official approval.
